Several studies have indicated that schizophrenic patients are likely to show high levels of nicotine dependence. Scientists from HSE Centre for Cognition and Decision Making, Institut Pasteur, the CNRS, Inserm and the ENS employed a mouse model to elucidate how nicotine influences cells in the prefrontal cortex. They visualized how nicotine has a direct impact on the restoration of normal activity in nerve cells (neurons) involved in psychiatric disorders such as schizophrenia. These findings were published in a paper that appeared in the journal Nature Medicine.
